Department of Psychology
University of New Mexico
Albuquerque, NM, USA
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Summary
Traumatic brain injury (TBI) often produces a focal cortical contusion
which evolves into a cyst and in rat this panecrosis is first detected
one day after TBI expanding markedly over the subsequent 15 days. We tested
the hypothesis that in traumatized cortex destined to evolve into a cyst,
neurons survive both the impact and "secondary" pathological events occurring
during the first few hours after traumatic brain injury (TBI). Using three
criteria for neuronal viability we found a large number of viable neurons
at the impact site surviving the impact for at least 3 days after injury.
Examination of cerebral blood flow after TBI indicated a persisting area
of ischemia at the impact site we suggests this is related to the slow
cortical panecrosis.
From: Symposium on Brain Damage and Functional Recovery The 2nd Internet
World Congress on Biomedical Science 1995 at http://www.inabis.org/
Introduction | Methods
| Results | Conclusion