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Selected Publications

2003-2005:

  • Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, Lein ES, Eadie B, Chun J., Lee K, and Gage FH. Methyl-CpG binding protein 1 is important for neurogenesis and genomic stability in adult neural stem cells. Proc. Natl. Aca. Sci. USA.  2003 100 (11): 6777-82.
  • Zhao X, Schaffer DV, Gage FH. Neurogenesis in adult brain: understanding the mechanism and regulation. “Stem cells in the Nervous System:Functional and Clinical Implications” (Springer-Verlag Berlin Heidelberg 2004).
  • Zhao X*, Farmer J*, van Praag H*, Wodtke K, Gage FH and Christie BR: Voluntary exercise reduces the threshold for the induction of long-term potentiation in the dentate gyrus in vivo. Neuroscience 2004, 124 (1): 71-9. (*, equal contribution)
  • Lein E.S. Zhao X., Aston C. and Gage F.H. Defing a Molecular Anatomy of the Hippocampus using DNA Microarrays and High-Throughput In Situ Hybridization J. Neurosci. 2004 24(15): 3879-3889.
  • van Praag H, Zhao X, Gage FH. Neurogenesis in the adult mammalian brain. The Cognitive NeurosciencesIII, (Michael S. Gazzaniga, Editor,MIT press 2004).

2006-2007

  • Zhao X, Lie DC, Gage FH. Adult-derived stem cells in treating Parkinson’s Diseases. Restorative therapies in Parkinson’s disease (2006, KLUWER Academic/Plenum Publishers, New York).
  • Basam Z. Barkho, Hongjun Song, James B. Aimone, Richard D. Smrt, Tomoko Kuwabara, Kinichi Nakashima, Fred H. Gage, and Zhao X#. Identification of astrocytes expressed factors that affect neural stem cell differentiation. Stem Cell and Dev 2006 15 (3): 407-421.
  • Smrt, RD. Eaves-Angenes J, Barkho BZ, Santistevan NJ, Aimone JB, Zhao C, Gage FH, and Zhao X#. Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons. (2007) Neurobiol. of Diseases 2007 Jul;27(1):77-89.
  • Zhao X#, Pak C, Smrt RD, Jin P#. “Epigenetics and Neural Developmental Disorders” Epigenetics 2007 Apr;2(2):130-138.

2008

  • Li X, Barkho BZ, and Zhao X#. Neural stem cells and neurogenic niche. (2008 Springer, Edited by Shi and Clegg) (in press)
  • Szulwach KE, Li X. Zhao X, and Peng Jin. MicroRNA and Stem Cell Epigenesis. Current Research and Perspectives in MicroRNAs (2008 Springer) (in press)
  • Li X, and Zhao X#. Epigenetic regulation of mammalian neural stem cells. Stem Cells and Dev 2008 (in press).
  • Allan AM, Liang X, Luo,Y, Pak C, LI, X, Szulwach KE, Chen D, Jin P, and  Zhao X#. The loss of methyl-CpG binding protein 1 leads to autism-like behavioral deficits 2008 Hum Mol Gen 2008 17(13):2047-57.
  • Li X., Barkho BZ, Luo Y, Smrt RD, Liu C, Kuwabara T, Gage FH, and Zhao X#. Epigenetic regulation of stem cell mitogen FGF-2 by Mbd1 in adult neural stem/progenitor cells. J. Biol. Chem. 2008 (in press)
  • Barkho BZ, Munoz A, Li, X, Li L, Cunningham LA, and Zhao X#. Endogenous Matrix Metalloproteinase (MMP)-3 and MMP-9 Promote the Differentiation and Migration of Adult Neural Progenitor Cells in Response to Chemokines. Stem Cells 2008 (in press)

(#, corresponding author)

 

Richard Smrt Stereotax

Coronal mouse brain sections