Kent A. Kiehl

Associate Professor
Email: kkiehl@unm.edu
Office: Logan 108
Phone: 925-4516
Curriculum Vitae

Degree Received
Ph.D., University of British Columbia, 2000

Research Interests
Research in my laboratory focuses on the clinical neuroscience of major mental illnesses, with special focus on criminal psychopathy, substance abuse, and psychotic disorders (i.e. schizophrenia). In association with The MIND Institute we use non-invasive techniques for measuring brain function, including event-related potentials (ERPs) and functional magnetic resonance imaging (fMRI). The goal of these studies is to elucidate and characterize the abnormal functional architecture believed to underlie these clinical disorders and to understand how psychological and/or pharmacological treatment modulates these neural processes. Ultimately, the goal of this research is to understand, diagnose, and effectively treat these clinical conditions.

My laboratory will be recruiting graduate students in clinical and cognitive psychology who are interested in psychopathy.

Kiehl Lab In The News

Suffering Souls: The Search for the Roots of Psychopathy, The New Yorker

Local Neuro-Imaging Research Has Potential To Save Taxpayer Money, Cut Social Costs, Albuquerque Journal

Investigating the Psychopathic Mind, Science

Scanning Psychopaths, Nature

New Mexico Scientist Studies Psychopaths Using Brain Scans, Albquerque Tribune

List of Recent Publications

Psychopathy Research

  • Levenson, M.R., Kiehl, K.A., & Fitzpatrick, C. (1995) Assessing psychopathic attributes in a noninstitutionalized population. Journal of Personality and Social Psychology, 68, 151-158. [pdf]
  • Kiehl, K. A., Smith, A. M., Forster, B.B., & Hare, R.D. (1995). Protocol for a functional MRI study of semantic and affective processing in psychopaths. Issues in Criminological & Legal Psychology, 24, 84.
  • Kiehl, K.A., Hare, R.D., Liddle, P.F. & McDonald, J.J. (1999). Reduced P300 responses in criminal psychopaths during a visual oddball task. Biological Psychiatry, 45, 1498-1507. [pdf]
  • Kiehl, K.A., Hare, R.D., McDonald, J. J., & Brink, J. (1999). Semantic and affective processing in psychopaths: An event-related potential (ERP) study. Psychophysiology, 36, 765-774. [pdf]
  • Kiehl, K.A. Smith, A.M., Liddle, P.F., & Hare, R.D. (2000). An event-related potential investigation of response inhibition in schizophrenia and psychopathy. Biological Psychiatry, 48, 210-221. [pdf]
  • Kiehl, K.A., Smith, A.M., Hare, R.D., Forster, B.B., & Liddle, P.F. (2001). Limbic abnormalities in affective processing in criminal psychopaths as revealed by functional magnetic resonance imaging. Biological Psychiatry, 50, 677-684. [pdf]
  • Bolla, K.I., Eldreth, D.A., London, E.D., Kiehl, K.A., Mouratidis, M., Contoreggi, C., Kurian, V., Cadet, J-L., Kimes, A.S., Funderburk, F.R., & Ernst, M. (2003). Orbitofrontal dysfunction in abstinent cocaine abusers performing a decision-making task. Neuroimage, 19, 1085-94. [pdf]
  • Kiehl, K.A., Smith, A.M., Mendrek, A., Forster, B.B., Hare, R.D., & Liddle, P.F. (2004). Temporal lobe abnormalities in semantic processing by criminal psychopaths as revealed by functional magnetic resonance imaging. Psychiatry Research: Neuroimaging, 130, 27-42. [pdf]
  • Bolla, K.I., Ernst, M., Kiehl, K.A., Mouratidis, M., Eldreth, D.A., Contereggi, C., Matochik, J., Kurian, M.S., Cadet, J.L., Kimes, A.S., Funderburk, F. & London, E.D. (2004). Prefrontal cortical dysfunction in abstinent cocaine abusers. Journal of Neuropsychiatry and Clinical Neuroscience, 16, 456-464. [pdf]
  • Kiehl, K.A., Bates, A. T., Laurens, K. R. & Liddle, P F. (2006). Psychopathy and semantic processing: An examination of the N400. Personality and Individual Differences, 40, 293-304. [pdf]
  • Kiehl, K.A. (2006). A cognitive neuroscience perspective on psychopathy: Evidence for paralimbic system dysfunction. Psychiatry Research, 142, 107-128. [pdf]
  • Kiehl, K.A., Bates, A. T., Laurens, K. R., Hare, R. D. & Liddle, P.F.(2006). Brain potentials implicate temporal lobe abnormalities in psychopathy. Journal of Abnormal Psychology [pdf]

Schizophrenia Research

  • Kiehl, K.A. Smith, A.M., Liddle, P.F., & Hare, R.D. (2000). An event-related potential investigation of response inhibition in schizophrenia and psychopathy. Biological Psychiatry, 48, 210-221. [pdf]
  • Kiehl, K.A. & Liddle, P.F. (2001). An event-related functional magnetic resonance imaging study of an auditory oddball task in schizophrenia. Schizophrenia Research, 48 (2-3), 159-171. [pdf]
  • Bates, A.T., Kiehl, K.A., Laurens, K.R., & Liddle, P.F. (2002). Error-related negativity and correct response negativity in schizophrenia. Clinical Neurophysiology, 113, 1454-63. [pdf]
  • Laurens, K.R., Ngan, E.T.C., Bates, A.T., Kiehl, K.A., & Liddle, P.F. (2003). Rostral anterior cingulate cortex dysfunction during error processing in schizophrenia. Brain, 126, 610-622. [pdf]
  • Calhoun, V. D., Kiehl, K. A., Liddle, P. F. & Pearlson, G. D. (2004). Aberrant localization of synchronous hemodynamic activity in auditory cortex reliably characterizes schizophrenia. Biological Psychiatry, 55, 842-849. [pdf]
  • Mendrek, A., Laurens, K.R., Kiehl, K.A., Ngan, E.T.C., Stip, E., and Liddle, P.F. (2004). Changes in distributed neural circuitry function in first episode schizophrenic patients during test-retest of a working memory task. British Journal of Psychiatry, 185, 205-214. [pdf]
  • Bates, A.T., Liddle, P.F., Kiehl, K.A., & Ngan, E.T.C. (in press). State dependant changes in error monitoring in schizophrenia. Journal of Psychiatry Research. [pdf]
  • Mendrek, A., Kiehl, K.A., Smith, A. M., Irwin, D., Forster, B.B., and Liddle, P.F. (in press). Dysfunction of a distributed neural circuitry in schizophrenic patients during working memory performance. Psychological Medicine. [pdf]
  • Laurens, K.R., Kiehl, K.A., Ngan, E.T.C, & Liddle, P.F. (2005). Disturbed orienting to salient novel stimuli during auditory oddball detection in schizophrenia. Schizophrenia Research, 75, 159-171 [pdf]
  • Kiehl, K. A., Stevens, M. C., Celone, K., Kurtz, M. & Krystal, J.H. (2005). Abnormal hemodynamics in schizophrenia during an auditory oddball task. Biological Psychiatry, 57, 1029-1040 [pdf]
  • Calhoun, V.D., Adali, T., Giuliani, N.R., Pekar, J.J., Kiehl, K.A., & Pearlson, G.D. (2006). Method for multimodal analysis of independent source differences in schizophrenia: Combining gray matter structural and auditory oddball functional data. Human Brain Mapping, 27, 47-62. [pdf]
  • Calhoun, V.D., Adali, T, Kiehl, K.A., Astur, R., Pekar, J.J. & Pearlson, G.D. (in press). A method for multi-task data fusion applied to schizophrenia. Human Brain Mapping. [pdf]

Obsessive Compulsive Disorder

  • Maltby, N., Tolin, D.F., Worhunsky, P., O’Keefe, T. M., & Kiehl, K. A. (2005). Dysfunctional action monitoring hyper-activates frontal-striatal circuits in obsessive-compulsive disorder: An event-related fMRI study. Neuroimage, 24, 495-503. [pdf]

Error Monitoring and Response Inhibition

  • Kiehl, K.A., Liddle, P.F., & Hopfinger, J.B. (2000). Error processing and the rostral anterior cingulate: An event-related fMRI study. Psychophysiology, 37, 216-223. [pdf]
  • Kiehl, K.A. Smith, A.M., Liddle, P.F., & Hare, R.D. (2000). An event-related potential investigation of response inhibition in schizophrenia and psychopathy. Biological Psychiatry, 48, 210-221. [pdf]
  • Liddle, P.F., Kiehl, K.A., & Smith, A.M. (2001). An event-related fMRI study of response inhibition. Human Brain Mapping, 12, 100-109. [pdf]
  • Bates, A.T., Kiehl, K.A., Laurens, K.R., & Liddle, P.F. (2002). Error-related negativity and correct response negativity in schizophrenia. Clinical Neurophysiology, 113, 1454-63. [pdf]
  • Laurens, K.R., Ngan, E.T.C., Bates, A.T., Kiehl, K.A., & Liddle, P.F. (2003). Rostral anterior cingulate cortex dysfunction during error processing in schizophrenia. Brain, 126, 610-622. [pdf]
  • Maltby, N., Tolin, D.F., Worhunsky, P., O’Keefe, T. M., & Kiehl, K. A. (2005). Dysfunctional action monitoring hyper-activates frontal-striatal circuits in obsessive-compulsive disorder: An event-related fMRI study. Neuroimage, 24, 495-503. [pdf]
  • Bates, A.T., Liddle, P.F., Kiehl, K.A., & Ngan, E.T.C. (in press). Effects of treatment on error-related negativity, error positivity and correct response negativity in schizophrenic patients. Journal of Psychiatry Research. [pdf]

Language Processing

  • Kiehl, K.A., Liddle, P.F., Smith, A.M., Mendrek, A. Forster, B.B., & Hare, R.D. (1999). Neural pathways involved in processing concrete and abstract words. Human Brain Mapping, 7, 225-233. [pdf]
  • Kiehl, K.A., Hare, R.D., McDonald, J. J., & Brink, J. (1999). Semantic and affective processing in psychopaths: An event-related potential (ERP) study. Psychophysiology, 36, 765-774. [pdf]
  • Vouloumanos, A., Kiehl, K.A., Werker, J. F., & Liddle, P.F. (2001). Detection of sounds in the auditory stream: fMRI evidence for differential activation to speech vs. non-speech. Journal of Cognitive Neuroscience, 13(7), 994-1005. [pdf]
  • Kiehl, K.A., Laurens, K.R. & Liddle, P.F. (2002). Reading anomalous sentences: An event-related fMRI study of semantic processing. Neuroimage, 17, 842-850. [pdf]
  • Kiehl, K.A., Smith, A.M., Mendrek, A., Forster, B.B., Hare, R.D., & Liddle, P.F. (2004). Temporal lobe abnormalities in semantic processing by criminal psychopaths as revealed by functional magnetic resonance imaging. Psychiatry Research: Neuroimaging, 130, 27-42. [pdf]

Emotion

  • Kiehl, K.A., Hare, R.D., McDonald, J. J., & Brink, J. (1999). Semantic and affective processing in psychopaths: An event-related potential (ERP) study. Psychophysiology, 36, 765-774. [pdf]
  • Kiehl, K.A., Smith, A.M., Hare, R.D., Forster, B.B., & Liddle, P.F. (2001). Limbic abnormalities in affective processing in criminal psychopaths as revealed by functional magnetic resonance imaging. Biological Psychiatry, 50, 677-684. [pdf]

Attention and Orienting (Oddball tasks)

  • McDonald, J.J., Ward, L.M., & Kiehl, K.A. (1999). An event-related brain potential analysis of inhibition of return. Perception and Psychophysics, 61, 1411-1423.
  • Kiehl, K.A., Hare, R.D., Liddle, P.F. & McDonald, J.J. (1999). Reduced P300 responses in criminal psychopaths during a visual oddball task. Biological Psychiatry, 45, 1498-1507. [pdf]
  • Kiehl, K.A., Laurens, K.R., Duty, T.L., Forster, B.B., & Liddle, P.F. (2001). Neural sources involved in auditory target detection and novelty processing: An event-related fMRI study. Psychophysiology, 38, 133-142. [pdf]
  • Kiehl, K.A. & Liddle, P.F. (2001). An event-related functional magnetic resonance imaging study of an auditory oddball task in schizophrenia. Schizophrenia Research, 48 (2-3), 159-171. [pdf]
  • Desjardins, A., Kiehl, K.A., & Liddle, P.F. (2001). Removal of confounding effects of global signal in functional MRI analyses. Neuroimage, 13, 751-758. [pdf]
  • Kiehl, K.A., Laurens, K.R., Duty, T.L., Forster, B.B., & Liddle, P.F. (2001). An event-related fMRI study of visual and auditory oddball tasks. Journal of Psychophysiology, 21, 221-240. [pdf]
  • Kiehl, K.A. & Liddle, P.F. (2003). Reproducibility of the hemodynamic response to auditory oddball stimuli: A six week test-retest study. Human Brain Mapping, 18, 42-52. [pdf]
  • Calhoun, V. D., Kiehl, K. A., Liddle, P. F. & Pearlson, G. D. (2004). Aberrant localization of synchronous hemodynamic activity in auditory cortex reliably characterizes schizophrenia. Biological Psychiatry, 55, 842-849. [pdf]
  • Laurens, K. R., Kiehl, K. A., & Liddle, P. F. (2005). A supramodal network encompassing limbic, paralimbic, and frontal and parietal association cortices mediates goal-directed attention. Human Brain Mapping, 24, 35-49. [pdf]
  • Kiehl, K.A., Bates, A. T., Laurens, K. R., Hare, R. D. & Liddle, P F. (in press). Brain potentials implicate temporal lobe abnormalities in psychopathy. Journal of Abnormal Psychology. [pdf]
  • Laurens, K.R., Kiehl, K.A., Ngan, E.T.C, & Liddle, P.F. (2005). Attention orienting dysfunction during salient novel stimulus processing in schizophrenia. Schizophrenia Research, 75, 159-171. [pdf]
  • Kiehl, K.A., Stevens, M. C., Laurens, K. R., Pearlson, G. P., & Liddle, P F. (2005). An adaptive reflexive processing model of neurocognitive function: Supporting evidence from a large scale (n=100) fMRI study of an auditory oddball task. Neuroimage, 25, 899-915. [pdf]
  • Kiehl, K. A., Stevens, M. C., Celone, K., Kurtz, M. & Krystal, J.H. (2005). Abnormal hemodynamics in schizophrenia during an auditory oddball task. Biological Psychiatry, 57, 1029-1040. [pdf]
  • Stevens, M. C., Calhoun, V.D., & Kiehl, K.A. (2005). Hemispheric differeneces in hemodynamics elicited by auditory oddball stimuli. Neuroimage, 26, 282-292. [pdf]
  • Calhoun, V.D., Pearlson, G.D., & Kiehl, K.A. (in press). Neuronal chronometry of target detection: fusion of hemodynamic and event-related potential data. Neuroimage. [pdf]
  • Stevens, M. C., Calhoun, V.D., & Kiehl, K.A. (in press). fMRI in and oddball task: Effects of target-to-target interval. Psychophysiology. [pdf]
  • Stevens, M. C., Laurens, K.R., Liddle, P.F., & Kiehl, K.A. (in press). The hemodyanmics of oddball processing during single-tone and two-tone target detection tasks. International Journal of Psychophysiology. [pdf]

Brain Imaging Methods Development

  • Forster, B.B., MacKay, A., Whittall, K. P., Kiehl, K.A., Smith, A.M., Liddle, P.F. & Hare, R.D. (1998). Functional MRI: The basics of the BOLD (blood oxygen level dependent) technique. Canadian Journal of Radiology, 49, 320-329.
  • Desjardins, A., Kiehl, K.A., & Liddle, P.F. (2001). Removal of confounding effects of global signal in functional MRI analyses. Neuroimage, 13, 751-758. [pdf]
  • Calhoun, V. D., Stevens, M. C., Pearlson, G. D., & Kiehl, K.A. (2004). fMRI analysis with the General Linear Model: Removal of latency-bias by incorporation of hemodynamic derivative terms. Neuroimage, 22, 252-257. [pdf]
  • Calhoun, V. D., Kiehl, K. A., Liddle, P. F. & Pearlson, G. D. (2004). Aberrant localization of synchronous hemodynamic activity in auditory cortex reliably characterizes schizophrenia. Biological Psychiatry, 55, 842-849. [pdf]
  • Calhoun, V. D., Adali, T., Stevens, M. C., Kiehl, K.A. & Pekar, J.J. (in press). Semi-blind ICA of fMRI: A method for utilizing hypothesis-derived time courses in a spatial ICA analysis. Neuroimage. [pdf]

Cetecean Research (Dolphin and Whales)

  • Szymanski, M.D., Bain, D., Kiehl, K.A., Henry, K., Pennington, S., & Wong, S. (1999). Killer whale (Orcinas orcas) hearing: Auditory brainstem response (ABR) and behavioral audiograms. Journal of the Acoustic Society of America, 106, 1134-1141. [pdf]

Current Graduate Lab Members

  Student/Research Interests
student
 Lora Cope
Functional and structural brain differences in incarcerated men
student
 Anne Lippert