G Proteins
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Course Outline
Study Notes
Readings

1: Hamm HE. How activated receptors couple to G proteins. Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):4819-21.

2: Horn F, van der Wenden EM, Oliveira L, IJzerman AP, Vriend G. Receptors coupling to G proteins: is there a signal behind the sequence? Proteins. 2000 Dec 1;41(4):448-59.

3: Busto R, Carrero I, Zapata P, Colas B, Prieto JC. Identification of functional somatostatin receptors and G-proteins in a new line of human foetal lung fibroblasts. Endocr Res. 2000 Aug;26(3):477-86.

4: Spiegel AM. Hormone resistance caused by mutations in G proteins and G protein-coupled receptors. J Pediatr Endocrinol Metab. 1999 Apr;12 Suppl 1:303-9.

5: Chetsawang B, Casalotti SO, Phansuwan-Pujito P, Kotchabhakdi N, Govitrapong P. Gene expressions of opioid receptors and G-proteins in pineal glands. Biochem Biophys Res Commun. 1999 Sep 7;262(3):775-80.

6: Coward P, Chan SD, Wada HG, Humphries GM, Conklin BR. Chimeric G proteins allow a high-throughput signaling assay of Gi-coupled receptors. Anal Biochem. 1999 Jun 1;270(2):242-8.

7: Djellas Y, Antonakis K, Le Breton GC. A molecular mechanism for signaling between seven-transmembrane receptors: evidence for a redistribution of G proteins. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10944-8.

8: Spiegel AM. Inborn errors of signal transduction: mutations in G proteins and G protein-coupled receptors as a cause of disease. J Inherit Metab Dis. 1997 Jun;20(2):113-21.

9: Bourne HR. How receptors talk to trimeric G proteins. Curr Opin Cell Biol. 1997 Apr;9(2):134-42.

10: Schmidt M, Rumenapp U, Keller J, Lohmann B, Jakobs KH. Regulation of phospholipase C and D activities by small molecular weight G proteins and muscarinic receptors. Life Sci. 1997;60(13-14):1093-100.

11: Marie JC, Rosselin G, Skoglund G. Pancreatic beta-cell receptors and G proteins coupled to adenylyl cyclase. Ann N Y Acad Sci. 1996 Dec 26;805:122-31; discussion 132.

12: Dessauer CW, Posner BA, Gilman AG. Visualizing signal transduction: receptors, G-proteins, and adenylate cyclases. Clin Sci (Lond). 1996 Nov;91(5):527-37.

13: Spiegel AM. Mutations in G proteins and G protein-coupled receptors in endocrine disease. J Clin Endocrinol Metab. 1996 Jul;81(7):2434-42.

14: Mullaney I, Caulfield MP, Svoboda P, Milligan G. Activation, cellular redistribution and enhanced degradation of the G proteins Gq and G11 by endogenously expressed and transfected phospholipase C-coupled muscarinic m1 acetylcholine receptors. Prog Brain Res. 1996;109:181-7.

15: Bygrave FL, Roberts HR. Regulation of cellular calcium through signaling cross-talk involves an intricate interplay between the actions of receptors, G-proteins, and second messengers. FASEB J. 1995 Oct;9(13):1297-303.

16: Gudermann T, Nurnberg B, Schultz G. Receptors and G proteins as primary components of transmembrane signal transduction. Part 1. G-protein-coupled receptors: structure and function. J Mol Med. 1995 Feb;73(2):51-63.

17: Reisine T, Woulfe D, Raynor K, Kong H, Heerding J, Hines J, Tallent M, Law S. Interaction of somatostatin receptors with G proteins and cellular effector systems. Ciba Found Symp. 1995;190:160-7; discussion 167-70.

18: Wong SK, Ross EM. Chimeric muscarinic cholinergic:beta-adrenergic receptors that are functionally promiscuous among G proteins. J Biol Chem. 1994 Jul 22;269(29):18968-76.

19: Wade SM, Dalman HM, Yang SZ, Neubig RR. Multisite interactions of receptors and G proteins: enhanced potency of dimeric receptor peptides in modifying G protein function. Mol Pharmacol. 1994 Jun;45(6):1191-7.

20: Polastron J, Jauzac P. Different subtypes of opioid receptors have different affinities for G-proteins. Cell Mol Biol (Noisy-le-grand). 1994 May;40(3):389-401.

21: Coughlin SR. Expanding horizons for receptors coupled to G proteins: diversity and disease. Curr Opin Cell Biol. 1994 Apr;6(2):191-7.

22: Baldwin JM. Structure and function of receptors coupled to G proteins. Curr Opin Cell Biol. 1994 Apr;6(2):180-90.

23: Insel PA. Adrenergic receptors, G proteins, and cell regulation: implications for aging research. Exp Gerontol. 1993 Jul-Oct;28(4-5):341-8.

24: Hadcock JR, Malbon CC. Agonist regulation of gene expression of adrenergic receptors and G proteins. J Neurochem. 1993 Jan;60(1):1-9.

25: Sabouni MH, Hussain T, Cushing DJ, Mustafa SJ. G proteins subserve relaxations mediated by adenosine receptors in human coronary artery. J Cardiovasc Pharmacol. 1991 Nov;18(5):696-702.

26: Bockaert J. Coupling of receptors to G proteins, pharmacological implications. Therapie. 1991 Nov-Dec;46(6):413-20.

27: Bockaert J. G proteins and G-protein-coupled receptors: structure, function and interactions. Curr Opin Neurobiol. 1991 Jun;1(1):32-42.

28: Manning DR. G proteins. Linkages with amine receptors. Neuropsychopharmacology. 1990 Oct-Dec;3(5-6):447-55.

29: Ashkenazi A, Peralta EG, Winslow JW, Ramachandran J, Capon DJ. Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell. Cell. 1989 Feb 10;56(3):487-93.