The easiest way to get Cadence up and running, is to use Centos7 in a VirtualBox VM. Cadence needs a good chunk of disk space, so setup the VM with about 100GB of space. https://vault.centos.org/7.9.2009/isos/x86_64/ I've been using the install media to setup packages for Cadence tools before hand. Insert the ISO image into the VM and setup the Media yum configuration to use your DVD ISO as a repository source for installation. [sbruno@sbruno-ece ~]$ df -k Filesystem 1K-blocks Used Available Use% Mounted on devtmpfs 1923232 0 1923232 0% /dev tmpfs 1940108 0 1940108 0% /dev/shm tmpfs 1940108 9760 1930348 1% /run tmpfs 1940108 0 1940108 0% /sys/fs/cgroup /dev/mapper/centos-root 52403200 34248908 18154292 66% / /dev/sda1 1038336 190680 847656 19% /boot /dev/mapper/centos-home 47285700 20636664 26649036 44% /home tmpfs 388024 24 388000 1% /run/user/1000 tmpfs 388024 0 388024 0% /run/user/0 /dev/sr0 10046218 10046218 0 100% /run/media/sbruno/CentOS 7 x86_64 Using the ISO CD, you can change the MEDIA yum repository to point at this directory: @sbruno-ece IC231]$ cat /etc/yum.repos.d/CentOS-Media.repo # CentOS-Media.repo # # This repo can be used with mounted DVD media, verify the mount point for # CentOS-7. You can use this repo and yum to install items directly off the # DVD ISO that we release. # # To use this repo, put in your DVD and use it with the other repos too: # yum --enablerepo=c7-media [command] # # or for ONLY the media repo, do this: # # yum --disablerepo=\* --enablerepo=c7-media [command] [c7-media] name=CentOS-$releasever - Media baseurl=file:///media/CentOS/ file:///media/cdrom/ file:///media/cdrecorder/ "file:///run/media/sbruno/CentOS 7 x86_64" gpgcheck=1 enabled=0 gpgkey=file:///etc/pki/rpm-gpg/RPM-GPG-KEY-CentOS-7 Install the following packages as they seem to be required by Cadence. I use sudo yum --disablerepo=\* --enablerepo=c7-media install gcc make kernel-devel kernel-headers \ redhat-lsb xterm mesa-libGLU motif libXp libpng12 glibc-devel libXScrnSaver apr apr-util \ compat-db47 xorg-x11-server-Xvfb openssl-devel 'xorg-x11-fonts-ISO8859*' xorg-x11-fonts-misc ksh Get credentials for the Cadence downloads and grab the Installscape tool. This is what Cadence wants to use for software management. Install the required tools for IC231: https://downloads.cadence.com/ESDWeb/Documents.eo?methodToCall=showDocument&entry=installScape [sbruno@sbruno-ece Downloads]$ cd /opt/cadence/installs/IC231/ [sbruno@sbruno-ece IC231]$ ll total 788 drwxr-xr-x. 2 sbruno sbruno 12288 Aug 21 16:28 bin -rw-rw-r--. 1 sbruno sbruno 91 Aug 21 16:29 CleanNC.log drwxr-xr-x. 2 sbruno sbruno 16384 Aug 21 16:28 data drwxr-xr-x. 252 sbruno sbruno 8192 May 6 2023 doc drwxr-xr-x. 6 sbruno sbruno 63 Aug 21 16:28 etc -rw-rw-r--. 1 sbruno sbruno 545054 Aug 21 16:18 Hotfix_IC23.10.080_lnx86.sdp -rw-rw-r--. 1 sbruno sbruno 665 Aug 21 16:18 ic_index.sdx -rw-r--r--. 1 sbruno sbruno 149439 Jul 10 11:24 IC_README -rw-r--r--. 1 sbruno sbruno 37694 Jul 9 14:19 IC_ReleaseInfo.pdf drwxrwxr-x. 6 sbruno sbruno 58 Aug 21 16:18 install drwxrwxr-x. 4 sbruno sbruno 39 Aug 21 16:18 installData drwxrwxr-x. 2 sbruno sbruno 135 Aug 21 16:29 iscape_logs drwxr-xr-x. 6 sbruno sbruno 55 Aug 21 16:23 oa_v22.61.015 drwxr-xr-x. 37 sbruno sbruno 4096 Jul 10 10:18 share lrwxrwxrwx. 1 sbruno sbruno 11 Aug 21 16:21 tools -> tools.lnx86 drwxr-xr-x. 57 sbruno sbruno 4096 Aug 21 16:28 tools.lnx86 Setup an evironment file for this install dir to setup your PATH, LD_LIBRARY_PATH and LICENSE_FILES: [IC231]$ cat ~/setup.sh export CDS=/home/ece525_student/cadence/installs/IC231/ export LD_LIBRARY_PATH=${CDS}/tools/lib:${LD_LIBRARY_PATH} export PATH=${CDS}/tools/dfII/bin:${CDS}/tools/dfII/bin/64bit:${CDS}/tools/bin:${PATH} export CDS_LIC_FILE=5280@ece46licsrv.ece.unm.edu export LM_LIC_FLE=5280@ece46licsrv.ece.unm.edu Source this file and then you should be able to run virtuoso from the command line.