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D1avid Peabody, Ph.D.
Molecular Genetics and Microbiology
University of New Mexico HSC
915 Camino de Salud NE
Albuquerque, NM 87131
 
Office: CRTC 316
Tel: (505) 272-0071
Fax: (505) 272-6029
E-mail: dpeabody@unm.edu

Keywords: RNA-protein interactions, translational regulation, virus assembly

Research Interests
Protein-RNA Interactions. The coat proteins of the RNA bacteriophages of E. coli interact with a stem-loop structure in viral RNA to repress replicase translation and to encapsidate the viral genome. Different RNA phage coat proteins possess similar tertiary structures but bind different RNA structures, providing a convenient model for understanding the basis of specificity in protein-RNA recognition. Making extensive use of genetics and biochemistry, we have characterized the RNA-binding sites of several coat proteins and have learned how to interchange their RNA-binding specificities. These studies are being extended to include investigation of coat protein folding and virus assembly.

Some basics of molecular biology:
How are biological macromolecules
synthesized? - Presentation

Bacteriophage MS2 VLPs for Nanobiotechnology - Presentation


 
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