LOGAN: LAWS OF LEARNING (Basic Processes) July 2004 FREE BEHAVIOR: Excitation Current Organism Independent Variables Contents Behavioral/Unnatural/Asocial/Emotionally-Neutral/Independent-Operation FECO>>1:00. Behavioral Effects of Acute Addictive Drugs FL****Ts1 FECO>>1:10A. ALC: Acute/Involuntary/Under-Influence FL****Ts1 Behavioral/Unnatural/Social/Emotionally-Neutral/Independent-Operation FECO>>1:11A. ALC: Effect on Aggressive Behavior FL****Ws1 Behavioral/Unnatural/Asocial/Emotionally-Neutral/Independent-Operation FECO>>1:10D. DRUGS: Acute/Involuntary/Under-Influence FL****Ts2 FECO>>1:20A. ALC: Acute/Involuntary/Not-Under-Influence FL****Tt1 FECO>>1:20D. DRUGS: Acute/Involuntary/Not-Under-Influence FL****Tt2 Behavioral/Unnatural/Asocial/Emotionally-Neutral/Interdependent-Operation FECO>>1:30A. ALC: Acute/Voluntary/Under-Influence FL****ts1 Behavioral/Unnatural/Social/Emotionally-Neutral/Interdependent-Operation FECO>>1:31A. ALC: Effect on Aggressive Behavior FL****ws1 Behavioral/Unnatural/Asocial/Emotionally-Neutral/Interdependent-Operation FECO>>1:30D. DRUGS: Acute/Voluntary/Under-Influcnce FL****ts2 FECO>>1:40A: ALC: Acute/Voluntary/Not-Under-Influence FL****tt1 FECO>>1:40D: DRUGS: Acute/Voluntary/Not-Under-Influrnce FL****tt2 FECO>>1:10A. ALC: Acute/Involuntary/Under-Influence FL****Ts1 HEO- ALC-->diplopia (lack of visual fusion) if no suppress image Cha,L.'51- HEO- Indiv diff re lo-dose ALC on reflex/equilibrium/coordinatn DSo,P.'52- DEO- Dose-dep decr in sex reflexes w/ALC incl incr Lat(ejac) - - Gan,WH'53- REO- P(audiogenic seizure) decr w/10% ALC injected B4 test - - - Dem,WN'54e REO- Audiogenic seizure decr w/.03, elim w/.08% blood ALC - - - Gre,LA'54+ HEO- Decr emotional tension (re startle/GSR) w/ALC w/out intox - Gre,LA'59+ REC- No effect of ALC on food intake 15-min after injection - - Eld,T.'60+ REA- Lo-dose ALC incr motionless beh, decr acty in open field - Eri,K.'68+ REA- ALC decr fear (incr open field acty) w/intragastric > drink Ami,Z.'70+ MEO- Self-directed aggressive beh incr-f(ALC ingested) - - - - - Cha,AS'70+ SEO- ALC sleep time w/bourbon > vodka, attrib to congeners - - - Blu,K.'71e HEx- Orientals > Whites re flushing, incr HR/discomfort w/ALC - Ewi,JA'74e SEx- Young (2-3-mo) shorter sleep time w/ALC re older (12-13-mo) Abe,EL'78- Above young also show greater pref, less decr acty w/ALC Abe,EL'78- REx- W/=dose, older subj higher blood ALC/hypotherm/motor impair Abe,EL'79+ REA- Dose-dep decr acty w/ALC but lo-dose ALC incr incr w/AMPH - Dun,PM'81+ REA- Mod dose ip ALC incr locomotor acty - - - - - - - - - - - - Cun,CL'83+ SEA- Less ALC-induced acty in long-sleep strain w/lo-dose ALC - Dud,BC'85+ HEO- Substantial ethnic diff in flushing R to ALC - - - - - - - Joh,RC'85e MEAH Post-opcond acty incr w/ALC, greater if decr Amt(reinf) - - Cox,WM'87e REO- Mild stress (handling) incr HR/body-temp R to ALC - - - - - Per,J.'87+ SEO- Re hypothermia, devel tolerance/cross-toler w/ALC/nicotine Col,AC'88e HECO ALC effect (eg elation/vigor) is-f indiv diff in pref - - - DWi,H.'88e FEO- Select lower environ temperature w/ALC - - - - - - - - - - OCo,CS'88e SEx- Strains bred re ALC sleep time diff in COC sensitivity - - DFi,CM'89e SEA- Locomotor acty incr w/ALC/COC, max if combine - - - - - - - Mas,J.'89e SEO- Strain diff in analgesia (re hotplate) w/ALC - - - - - - - Yir,R.'89+ SEx- Infer mult genetic R to ACL from patterns of strain diff - Dud,BC'90+ SEO- Lo-dose ALC decr stress-induced immobility in swim test - - Hil,LA'90e SEO- Rotarod ataxia w/ALC w/short sleep < long, elim w/Ro15-4513 Sti,A.'90e HEC- Decr reaction to ALC w/children of alcoholics - - - - - - - Ant,RM'91+ SEA- Qual/quant strain diff in biphasic effect ALC dose on acty Dud,BC'91e REO- Strain diff in ALC tolerance re motor impair not-f(handling Kor,ER'91e FECO>>1:11A. ALC: Effect on Aggressive Behavior FL****Ws1 REO- ALC incr Lat(mount/intromission/ejaculation) w/incr freq - Dew,DA'68- REO- Aggressive beh decr w/ALC, incr w/caffeine - - - - - - - - Cap,H.'70+ REO- ALC incr sex motiv, incr Lat(ejaculation) - - - - - - - - - Har,BL'70- FEO- Aggressive display incr w/ethanol, decr w/bourbon/congeners Ray,AE'71+ FEO- Aggression re intruder incr-decr-f(dose ALC) - - - - - - - Pee,HV'73e REx- W/monosex pairs, ALC decr social, not nonsocial acty - - - Krs,M.'74+ REO- W/mating females, ip ALC decr freq, incr duration lordosis Mer,A.'74e SEx- Concl: ALC incr beh stimulated by test sit (eg fight/sex) - Cut,MG'75e REO- Shock-elicited fighting incr w/lo/mod-dose ALC, decr w/hi - Wei,MK'75- REO- Observe attack/defensive fight beh w/omit sched food reinf Mic,KA'77+ Lo dose ip ALC to dominant O incr attack in above Mic,KA'77+ Hi dose ip ALC to dominant O decr attack in above Mic,KA'77+ Hi dose ip ALC to submissive O decr defense in above Mic,KA'77+ SEO- Lo-dose ALC incr attack beh in neutral, not in home cage - Mic,KA'80+ REOH W/food dep, lo-dose ALC decr shock-elicited aggression - - Tra,JL'80e MEO- Lo-dose ALC decr, hi-dose incr despair R w/peer separation Kra,GW'81e TEO- ALC to dominant O decr fighting; no effect on submissive - Wal.DL'85+ MEO- Lo-dose ALC incr, hi-dose decr aggressive beh by dominant - Win,JT'85+ No effect of ALC on aggressive beh of subordinate O Win,JT'85+ REO- Lo-dose incr, hi-dose decr defensive attack beh w/wild O - Bla,RJ'86e REO- Lo-dose ALC incr female attack beh w/small/large intruder - Bla,DC'87e Hi-dose ALC decr female attack beh w/large not small foe Bla,DC'87e REO- ALC decr male offensive beh, incr offensive against females Bla,RJ'87e REO- Lo-dose ALC incr male aggressn only w/intermed-aggressive O Bla,RJ'87e Hi-dose ALC decr aggressive beh re intruder Bla,RJ'87e REx- ALC decr freezing re cat S, no effect on attack re rat S - Bla,RJ'89e SEA- ALC incr locomotor acty, decr social interaction - - - - - Dur,MJ'89e REO- ALC decr male sex beh, but lo-dose disinhib sex beh - - - - Pfa,JG'89+ REO- ALC incr attack beh by resident, defense beh by intruder - Pet,JT'90+ FECO>>1:10D. DRUGS: Acute/Involuntary/Under-Influence FL****Ts2 RWAO Acty incr-decr-f(sc benzedrine sulphate), esp w/inactive O Bro,CW'38+ REO- Caffeine incr P(audiogenic seizure) - - - - - - - - - - - - Sne,TJ'42e SEO- Injected nicotine facil audiogenic seizure - - - - - - - - Fri,H.'54+ REO- Lo-dose caffeine has stimulating effect on sexual beh - - - Zim,PG'58+ REA- MORPH incr explor beh w/novel S, decr adaptation - - - - - Bea,HD'59- REA- 1 mg/kg AMPH incr acty w/young, not w/older O - - - - - - - Ver,F.'61+ REO- Greater MORPH analgesic effect w/addiction-prone O - - - - Nic,JR'63+ MEA- Acty decr-f(dose d-AMPH) - - - - - - - - - - - - - - - - - Ale,M.'65+ REA- No effect of lo-dose, but hi-dose MORPH decr run acty - - - Col,LB'65- SEC- Milk intake decr-f(dose d-AMPH), w/decr not-f(food dep) - - Bou,DC'69+ SEA- d-AMPH decr explor acty - - - - - - - - - - - - - - - - - - Wak,HG'69+ SEA- AMPH decr explor acty in novel context - - - - - - - - - - Bai,JG'71- OEO- m-AMPH incr social R/imprinting - - - - - - - - - - - - - - Raj,DW'71+ REO- Mod, not lo or hi, dose novel THC incr shock-induced fight Car,B.'72+ REO- Shock-elicited fighting incr-decr-f(dose m-AMPH) - - - - - Cro,TJ'72- MEA- m-AMPH incr spon acty in both lite/dark phase of cycle - - Ibu,N.'72- REO- No effect of ip THC on shock-elicited fighting - - - - - - Man,FJ'72+ THC decr Rate(OpR) w/FI sched Man,FJ'72+ REA- Lo-dose MORPH incr locomotor acty, qual diff from AMPH - - Ayh,IH'73+ REA- Wheel-run acty incr-decr-f(dose m-AMPH) during 1st hr - - - Jak,LF'73+ REA- d-AMPH incr locomotor acty but decr explor beh - - - - - - Rob,T.'73+ REA- d-AMPH incr horizontal/vertical stereotypy in open field - Dan,PC'74+ REA- Nicotine decr wheel acty if hi basal rate, no effect if low Mel,CJ'74e REO- THC decr defensive beh of submissive, attack by dominant - Mic,KA'74+ REA- d-AMPH incr acty, esp w/food dep - - - - - - - - - - - - - Sim,LL'74- AEO- Concl: Cannibus incr "irritable", decr intermale aggression Abe,EL'75- SEx- No correl strain diff in MORPH effect on acty/tolerance/dep Eid,E.'75e REO- 6 mg/kg sc MORPH did not decr pain thresh w/aversive ESB - Ros,JP'75+ REx- Genz: AMPH incr locomotor acty and stereotyped beh - - - - Gro,PM'76+ DEO- Alter food dominance w/d-AMPH to dominant O - - - - - - - - Wer,J.'76e SEx- Re hot-plate/locomotor acty, MORPH effect w/C57 not w/DBA - Col,RL'78+ REA- Beh stereotypy incr-f(dose AMPH), less w/novel S/context - Rus,RL'78+ mEA- Dose-related decr in locomotor acty w/d-AMPH - - - - - - - Isa,W.'79+ REA- AMPH incr acty w/females > males - - - - - - - - - - - - - Sch,BF'79+ REA- Open-field explor incr w/caffeine, not w/nicotine - - - - - Lok,WH'84+ MEO- d-AMPH decr affiliatn beh, incr aggressn in hi/lo-rank O - Smi,EO'84+ RER- Caffeine incr wheelrunning, esp if exper w/drug + running - Mel,CJ'85e SEA- Estab genetic role in effect of MORPH on acty - - - - - - - Mur,T.'85+ rEO- Lo dose MORPH incr play beh, w/some reversal in dominance - Pan,J.'85e REA- Locomotor acty incr w/heroin/AMPH/caffeine - - - - - - - - Swe,NR'85e Naloxone decr acty w/heroin, less w/AMPH, not w/caff Swe,NR'85e REA- W/nontolerant O, nicotine decr rearing, mod locomotion - - Jer,A.'87+ REO- MORPH B4 shock exposure decr cond autoanalgesia - - - - - - Roc,J.'87+ TEA- MORPH-elicited hyperacty elim w/naloxone - - - - - - - - - Sch,P.'87+ HEO- Hi-dose AMPH incr BP but no effect on aggressive beh - - - Bee,DA'88e REC- MORPH incr intake/pref for isotonic saline vs H2O - - - - - Ber,M.'88e MEO- im AMPH incr w/drawal from social encounters (marmoset) - - Ann,LE'89e SEA- Lo-dose COC decr locomotor acty; hi-dose incr acty - - - - Geo,FR'89- REO- d-AMPH-->Stereotype diving in H2O, elim w/preexpose to tank Pet,AD'89+ REx- Indiv diff in acty w/novel context correl w/resp to AMPH - Pia,PV'89e REO- Signif stereotypy w/lo-dose d-AMPH - - - - - - - - - - - - See,RJ'89+ SEA- Locomotor acty incr w/hi-dose COC only w/short-sleep O - - Geo,FR'90+ mEO- Acute d-AMPH-->hypoacty w/raised motionless "floating limb" Lev,ED'90e REO- Nicotine incr reflex startle to noise S - - - - - - - - - - Acr,JB'91e REA- Lo-dose COC decr acty w/strain diff in effect - - - - - - - Geo,FR'91- SEA- COC incr locomotor acty w/both short/long sleep O - - - - - Jon,BC'91e REx- Indiv diff in acty w/novel context correl w/self-admin AMPH Pia,PV'91e SEA- Breed strains re depression/activation w/nicotine/COC - - - Smo,A.'91+ MEP- Induce adjunctive iv saline w/FI food or iv COC self-reinf Gra,KA'92+ FECO>>1:30A. ALC: Acute/Voluntary/Under-Influence FL****ts1 HDXO Indiv diff in effect of ALC, decr-f(gen competence) - - - - Hol,HL'24- HEO- ALC decr peripheral color fields - - - - - - - - - - - - - Pet,HB'43- CEC- ALC decr complex lrnd feeding beh, but facil if hi conflict Mas,JH'44- OEO- Indiv diff in olfactory thresh for ALC in blowfly - - - - - Det,VG'52+ HEO- ALC-->decr hunger/taste acuity - - - - - - - - - - - - - - Mar,NR'52+ HEO- ALC decr/elim color in after-image - - - - - - - - - - - - Pop,NA'54+ REA- Running wheel acty not-f .2cc 64% oral ALC - - - - - - - - Lew,DJ'59+ HEO- ALC decr GSR, esp w/hi emot react O - - - - - - - - - - - - Lie,GA'59+ HEO- ALC incr RT, counteract w/shock stress - - - - - - - - - - Fra,M.'75e HEO- ALC decr peripheral vision only if simult info-proc task - Mos,H.'75+ HEx- Marked indiv diff in various Rs to ALC, partly genetic - - Ree,TE'86- HEO- ALC incr monologue speech in isolation, decr nonverbal beh Hig,ST'88+ HEO- Blood ALC incr visual detection threshold w/female > male - Ava,LL'90- HEH- Less stress-induced incr HR w/lo-dose ALC, esp w/hi anxious Vog,WH'91+ FECO>>1:31A. ALC: Effect on Aggressive Behavior FL****ws1 MEx- In social gp, ALC incr play-fighting, hetero-to-autosex beh Cro,TJ'75e HEO- Lo-dose ALC decr, hi- incr physical aggressn, vodka>bourbon Tay,SP'75+ HEx- Vol lo-dose ALC during social hr incr perf/morale/sleep - - Mis,BL'76e HEO- Physical aggression incr-f(Amt(ALC)) - - - - - - - - - - - Tay,SP'76e HSOE ALC incr male aggression in RT only w/threat by opponent - Tay,SP'76e HSOE ALC incr male aggression (shock), decr w/social pressure - Tay,SP'77+ HSOE ALC incr male aggression in RT w/w/out frustration - - - - Tay,SP'77e HEO- ALC incr aggressn re shock-other, w/w/out aversive conting Zei,A.'79+ HEO- W/shy male O, ALC impair social interaction w/female - - - Kea,TM'80+ HSOE ALC incr male aggression re injurious shock if hi provocatn Tay,SP'80e HEx- Re HR/GSR/beh, ALC incr male interact perf w/silent femal Lip,TR'81e Above effect incr-f(dose), less w/hi-ALC-tolerant O Lip,TR'81e HEO- Incr in aggressive beh (counter-punish other) w/lo-dose ALC Che,DR'85e HEx- ALC incr aggressn (noise to opponent), decr stress w/noise Bon,A.'89+ HEx- ALC decr social anxiety, incr verbal acty in small groups - Lin,B.'89+ HSOE Social pressure to aggress incr shock in RT only w/ALC - - Tay,SP'89+ HEO- Concl: ALC-->incr aggression, is-f(method/parameters) - - - Bus,BJ'90+ HSOE Male aggression w/w/out provocation not-f(wine) - - - - - - Gus,R.'90- HSOE W/supervise scan, female use non-aggressive fdbk not-f(ALC) Gus,R.'92- FECO>>1:30D. DRUGS: Acute/Voluntary/Under-Influcnce FL****ts2 HEO- Both males/females said marijuana incr sex desire/pleasure Kof,WC'75- hEx- W/prepubertal boys, caffeine incr vigilance/motor acty - - Elk,RN'81e HEO- d-AMPH incr amt monologue speech emitted - - - - - - - - - Hig,ST'89+ HEO- COC incr digit-symbol perf, w/no effect on lrng R-seq - - - Hig,ST'90e HEO- Hi-dose caffeine incr intel-test perf w/extravert O only - Gup,U.'91- FECO>>1:40A: ALC: Acute/Voluntary/Not-Under-Influence FL****tt1 HEO- Indiv diff in ALC dose nec to decr hunger/olfactory acuity Irv,DL'52e REA- No effect ALC diet on free acty; decr intake at hi concen - Bar,SI'88- HEO- ALC decr amt/accuracy of eyewitness memory of staged crime Yui,JC'90+