LOGAN: LAWS OF LEARNING (Basic Processes) July 2004 FREE BEHAVIOR: Excitation Independent Historic Organism Variables Contents Behavioral/Unnatural/Asocial/Emotionally-Neutral/Independent-Operation FEHO>>1:00. Behavioral Effects of Addictive Drugs FN****Ts1 FEHO>>1:10A. ALC: Chronic/Involuntary/Under-Influence FN****Ts1 FEHO>>1:10D. DRUGS: Chronic/Involuntary/Under-Influence FN****Ts2 FEHO>>1:20A. ALC: Chronic/Involuntary/Not-Under-Influence FN****Tt1 FEHO>>1:20D. DRUGS:Chronic/Involuntary/Not-Under-Influence FN****Tt2 Behavioral/Unnatural/Asocial/Emotionally-Neutral/Interdependent-Operation FEHO>>1:30A. ALC: Chronic/Voluntary/Under-Influence FN****ts1 FEHO>>1:30D. DRUGS: Chronic/Voluntary/Under-Influcnce FN****ts2 FEHO>>1:40A: ALC: Chronic/Voluntary/Not-Under-Influence FN****tt1 FEHO>>1:40D: DRUGS: Chronic/Voluntary/Not-Under-Influrnce FN****tt2 Relevant uncoded root-abstracts Relevant(?) unabstracted/uncoded literature FEHO>>1:10A. ALC: Chronic/Involuntary/Under-Influence FN****Ts1 REO- Re inhib of spinal R, devel ALC tolerance w/practice w/ALC Jor,HA'84+ Above w/intact/spinal O, w/genz tolerance to new context Jor,HA,84+ REO- Devel tolerance to hypothermic, not tachycardic R to ALC - Per,J.'85+ REO- Tolerance to anticonvulsant ALC effect not attrib to cond - Pin,JP'85+ REO- ALC decr tail-flick UR in spinally-transected O - - - - - - Jor,HA'86e Devel lrnd ALC tolerance w/practice, genz to MORPH Jor,HA'86e Note: Devel pharmacol tolerance w/ALC exposure, Jor,HA'86e but no genz to MORPH Jor,HA'86e SEx- Devel tol w/chronic ALC/nicotine, w/some cross-tolerance - Bur,JB'88e SEA- 2/3rd O show incr acty w/ALC/d-AMPH, incr w/chronic ALC - - Mas,J.'88+ REO- Handling stress incr hypothermia w/ALC and devel tolerance Per,J.'88+ SEA- 24-h after 3-wk ALC diet, ALC stimulate incr acty - - - - - Mid,LD'89e REO- Acoustic startle decr w/chronic ALC, incr w/w/drawal - - - Ras,S.'92e FEHO>>1:10D. DRUGS: Chronic/Involuntary/Under-Influence FN****Ts2 REO- Devel analgesic tolerance to MORPH w/single dose - - - - - Kor,C.'68+ REC- Devel anorexigenic tolerance w/AMPH given B4, not after eat Car,PL'71+ REA- Devel beh tolerance to m-AMPH re hyperacty over 6-wk trtmt Bel,DS'74e XEO- Chronic m-AMPH-->Specific stereotypy in rat/cat/monkey - - Ell,EH'74+ REA- W/20mg/kg ip MORPH daily-->Decr acty->tolerance->then excit Bab,M.'75e REx- Daily nicotine-->Tolerance re acty/EEG - - - - - - - - - - Hub,JE'75+ SEO- Devel analgesic tolerance/cross-tolerance w/MORPH/AMPH - - Lit,HJ'75+ REA- Chronic caffeine-->Tolerance to incr acty caffeine effect - Fin,IB'88- SEA- Acute AMPH decr, chronic incr acty w/BALB (not stim w/AMPH) Log,L.'88e REO- Acq MORPH analgesic tolerance faster w/lo-dose/long ITI - - Daf,RI'89e REW- Acq context-specific nicotine tolerance re tail w/drawal R Eps,LH'89e RECH Acq context-specific nicotine tolerance re decr milk intake Cag,AR'91e FEHO>>1:20A. ALC: Chronic/Involuntary/Not-Under-Influence FN****Tt1 REO- Incr P(audiogenic seizure) during w/drawal from chronic ALC Fre,G.'71+ SEN- W/drawal after 6-d ALC-->tremor/ataxia and abnormal EEG - - Wal,DW'74+ REA- Incr acty R w/novel S 8-d after recover from short-term ALC Bon,NW'75+ REx- ALC dependence w/10-d forced intake, w/incr audio seizure Hun,BE'75e REO- Symptoms re ALC w/drawal decr by acute ALC, gradual w/draw Poh,LA'75e REA- W/drawal from chronic ALC-->Anxiety (decr open-arm acty) - Lal,H.'92e FEHO>>1:20D. DRUGS:Chronic/Involuntary/Not-Under-Influence FN****Tt2 REO- During w/drawal from 15-d ip MORPH, strain diff in aggressn Bor,LA'70- SEx- Chronic 5-mg/kg ip d-AMPH-->Abnormal beh (hyperacty/autism) Car,J.'74- REO- Signif w/drawal (re naloxone) after 3-d daily lo-dose MORPH Fru,K.'75- MEA- Chronic daily d-AMPH incr acty, w/decr acty during w/drawal Hou,VP'75- SEO- MORPH w/drawal severity w/ALC short > long sleep O - - - - Hor,GP'82+ FEHO>>1:30A. ALC: Chronic/Voluntary/Under-Influence FN****ts1 HEO- Attrib alcohol diplopia to impaired binocular fusion reflex Bre,GA'56e REx- Rate devel physiol/beh tolerance incr w/repeat drug cycles Kal,H.'78e HEx- Wide indiv diff in state-dependent-recall w/ALC - - - - - - Ken,TA'87e Above diff pos correl w/drinking history, re blackouts Ken,TA'87e REx- W/repeated 2-wk binge ALC, accel beh/physiol tolerance - - Mai,DM'87+ HEO- Naloxone decr ALC analgesia re cold-press only w/drinkers - Cut,HS'88+ REO- Initial ALC sensitivity (recover reflex) correl w/tolerance Gra,KA'90e FEHO>>1:40A: ALC: Chronic/Voluntary/Not-Under-Influence FN****tt1 HEO- Delerium tremens is-f excessive ALC or abrupt w/drawal - - Lec,R.'52- SEx- ALC w/drawal severity w/long sleep < short sleep strain - - Gol,DB'76+ W/drawal severity not correl w/sleep time in population Gol,DB'76+ REO- Neg correl initial ALC sensitivity w/dependence w/exposure Mar,P.'85+ MEC- W/hi self-admin iv ALC in females, disrupt menstrual cycle Mel,NK'85e Above w/3 of 5 O, devel dependence/sickness/death Mel,NK'85e MEC- ALC self-admin lower during menstruation - - - - - - - - - Mel,NE'86e SEC- W/ALC diet, hi intake, severe w/drawal w/short sleep O - - Gil,DM'88+ REO- Chronic ALC incr shock-induced fighting; incr w/w/drawal - Rou,S.'92e FEHO>>1:40D: DRUGS: Chronic/Voluntary/Not-Under-Influrnce FN****tt2 REO-tt2_W/drawal from chronic MORPH-->Incr shock-induced aggression Dav,WM'71+ Relevant uncoded root-abstracts Relevant(?) unabstracted/uncoded literature