ANTH 450/550.  Population Genetics

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Anthropology 450/550:
Topics in Population and Quantitative Genetics

Fall 1998                                    

Instructor: Dr. Joseph F. Powell             Office:       Anthropology Rm. 162
Phone:       277-1538                                Email:      jpowell@unm.edu



Brief Description:

This course will provide a basic overview of population and quantitative genetics, which are concerned with the processes and mechanisms by which evolutionary change occurs. Students will be introduced to theoretical models of nonrandom mating, random genetic drift, mutation, gene flow/migration, and natural selection, as well as to the genetic basis of quantitative traits. The course will also focus on the application of these models in the study of genotypic and phenotypic variation in past and present human populations.

Students must be familiar with the basic concepts of human biology and genetics, and must have basic mathematical skills. A background in computer-assisted data analysis or statistics will be helpful but is not required.


Grading and Course Requirements:

Grading will be based on a series of take-home problem sets (45%), in-class tests (25%), and a final research paper (30%). Students enrolled in 550 must produce a paper of publishable quality based on an analysis of actual genotypic and/or phenotypic data from a human population. Students enrolled in section 450 may present the results of data analysis or may, with instructor approval, produce an intensive literature review or survey of current research on an appropriate subject. Students should note that problem sets will be docked one letter grade for each day they are late; final papers will not be accepted after the due date.


Textbooks:

Falconer, D.S., and T.F.C. MacKay. 1989. Introduction to Quantitative Genetics. Fourth edition. Essex,
     England: Longman Scientific and Technical. (Denoted as "F&M" in course schedule)

Hartl, D.L., and A.G. Clark. 1997. Principles of Population Genetics. Third edition. Sunderland, MA: Sinauer
     Associates. (Denoted as "H&C" in course schedule)