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Lactate Formation

Explain the Lactate Formation.
After glycolysis 2 NADH+H and 2 pyruvate are two of the molecules formed. During resting and steady state conditions the NADH+H+ molecules go into the inner membrane of the mitchondrion and reduce FAD to FADH2. Pyrvate goes directly into the mitochondrion matrix. However, during strenuous exercise the energy demands exceed the oxygen supply in the ETC, causing a back-up in the ETC. NADH+H+ is inhibited and therefore donates its hydrogens to pyruvate, reducing pyruvate to lactate. NAD+ can then return to glycolysis to pick-up more hydrogens.
Robert Parra, 2006


Question: Does Lactate Production Occur in the Mitochondrion or the Cytoplasm of the cell?


Answer: Cytoplasm of the cell.