Course Outline
Study Notes
Readings
593eee Labs
Study Guides | |
GENERAL ENVIRONMENTAL PHYSIOLOGY
 | What systems of the body are perturbed during exposure to different
environmental conditions? |
| What are the applications of knowledge of the body's responses during
exposure to abnormal environments? |
HYPOXIA AND HYPOBARIA
Basic Physiology
| Calculate atmospheric and alveolar partial pressures of O2 and
CO2 for the conditions: |
a) sea level, and 24% RH @ 24 ° C, ; b)
Albuquerque (5,000 ft @ 630 mmHg) and 15% RH @ 24 °
C ; b) Pikes Peak (4,300 m) and 15% RH @ 5 ° C
| Interpret the O2-Hb Dissociation curve. |
| Understand the Bohr effect. |
| Understand the potential diffusion limitation for oxygen for the blood-gas
interface of the lung and peripheral tissues. |
| Why is hyperventilation at altitude beneficial for PaO2? |
| What are the relationships between end-tidal, alveolar, and arterial gas
partial pressures? |
| Be able to calculate arterial concentrations of oxygen, for given PaO2
and [Hb] conditions. |
Exercise at Altitude
| Understand the implications of a decreasing pulmonary transit time to the
difference between PAO2
and PaO2. |
| What are the functional implications of a widening PAO2
and PaO2? |
| Compared to acute exposure, does VO2max
increase after acclimatization to high altitude? Why? |
| Does exercise performance increase after acclimatization to high
(>10,000 ft) altitude? Why? |
| At what altitude does VO2max decline from
sea level values? Why? |
| How does acute altitude exposure alter the blood buffering capacity? |
| What happens during the renal compensation phase of altitude exposure? |
| Be able to list the central cardiovascular alterations to exercise during
acute altitude exposure. |
AMS, High Altitude Pulmonary Edema (HAPE), and Cerebral
Edema
| What are HAPE and HACE ? |
| What are the best ways to avoid the development of HAPE during ascent to
high altitude? |
| What are the best treatments for the early symptoms of HAPE? |
| What are the symptoms of acute mountain sickness (AMS)? |
| Why does sleeping at altitude exacerbate AMS? |
Training at Altitude: Adaptations and Exercise
Performance
| Does altitude training benefit seal level performance? Does altitude training benefit
performance at altitude ? |
| Why do people train at altitude? |
| What athletes (regarding distance/duration) may benefit from altitude
training? |
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